Recently published papers in the field of molecular evolution

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Recently published papers: Topical issues in pharmacology

The use of pharmacological agents in intensive care units (ICUs) is ever on the increase, with novel therapies appearing in the literature regularly. The complexities of polypharmacy are a challenge to the intensivist, and any guidance as to which drugs to use, when to use them and how much to use is always welcome. Happily, therefore, over the past 2 months a number of interesting papers and a...

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Recently published papers: From superbugs to superbowl

Several papers are discussed including the CARP (Coronary Artery Revascularisation Prophylaxis) trial, examining the role, if any, of preoperative coronary revascularisation and a study examining the heart rate in the intensive care unit (ICU) population. We also take a look at infections in the ICU with particular regard to a recent study which examined isolating patients with methicillin-resi...

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Recently published papers: predictors, pressors and poietins

Simple, sensitive and specific predictors of mortality in the critically ill remain elusive goals, and brain natriuretic peptide and venous lactate are the subjects of recent studies. The role of vasopressin in sepsis continues to be the focus of much research interest. Dose ranging studies, potential adverse effects, and selective V1 agonists are discussed below in recent trials. Finally the u...

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Recently published papers: inflammation, elucidation, manipulation?

The search for the marker in sepsis and inflammation continues. Perhaps when we do find it we may be able to alter and influence the underlying pathophysiology of sepsis. Many reports from those who believe that this may lie in the hypothalamic–pituitary–adrenal axis have recently been published. Manglik and colleagues [1] looked into secondary adrenocortical insufficiency in patients who prese...

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Recently published papers: Heavyweight problems in the intensive care unit?

The management of the obese patient in intensive care is fraught with difficulty, or so conventional wisdom would have us believe. Two recent studies add to the growing evidence that the obese patient is not significantly disadvantaged in terms of outcome following intensive care admission. Another study highlights the increasing burden of end-stage renal disease on intensive care unit resource...

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ژورنال

عنوان ژورنال: Journal of Molecular Evolution

سال: 1983

ISSN: 0022-2844,1432-1432

DOI: 10.1007/bf02099977